Hims is generally the cheaper of the two for GLP-1 weight loss, pricing compounded semaglutide around $199/month versus Henry Meds at approximately $145–$199/month all-in (Henry Meds's pricing structure varies by plan and has historically avoided a separate consultation fee). Both prescribe the same active ingredients through licensed providers and accredited compounding pharmacies. Luma Health undercuts both at $90/month for compounded semaglutide and $165/month for tirzepatide, with no consultation fee and no contract.
Hims vs Henry Meds: Quick Overview
If you're comparing Hims and Henry Meds for GLP-1 weight loss in 2026, you're evaluating two of the more visible telehealth platforms in the compounded medication space. Both prescribe GLP-1 receptor agonists — primarily compounded semaglutide and compounded tirzepatide — through licensed providers and accredited compounding pharmacies. The medications themselves are pharmacologically identical regardless of which platform writes the prescription. What differs is what you pay, how you interact with providers, and what level of clinical support surrounds your treatment.
Hims, officially Hims & Hers Health, is a large, publicly traded telehealth company operating across dozens of health categories including hair loss, skincare, mental health, and sexual health. Their weight loss division prescribes compounded GLP-1 medications through an app-based, primarily asynchronous consultation model. Henry Meds is a more narrowly focused telehealth platform that has positioned itself around bundled, relatively transparent GLP-1 pricing with a web-based consultation workflow and direct-to-patient medication delivery.
Both platforms deliver legitimate medications prescribed by licensed providers. The differences that matter most come down to monthly cost at maintenance doses, contract flexibility, and the depth of clinical support patients receive throughout treatment. We include Luma Health in this comparison because at $90/month for compounded semaglutide and $165/month for compounded tirzepatide, it represents a meaningfully different price point that patients evaluating Hims and Henry Meds should be aware of.
Head-to-Head Comparison Table
| Factor | Hims | Henry Meds | Luma Health |
|---|---|---|---|
| Semaglutide Price | $199/mo | $145/mo | $90/mo |
| Tirzepatide Price | $199–$249/mo | $199/mo | $165/mo |
| Consultation Fee | Included | None (bundled) | Included |
| Contract Required | Monthly | Monthly | Monthly |
| Platform Type | App-based, asynchronous | Web-based | Web + messaging |
| Provider Focus | Multi-category | Weight loss focus | Metabolic health specialist |
| Shipping | Included | Included | Free, 2–3 days |
| 12-Mo Semaglutide Total | $2,388/yr | $1,740/yr | $1,080/yr |
| 12-Mo Tirzepatide Total | $2,388–$2,988/yr | $2,388/yr | $1,980/yr |
⚠ Pricing Note
Telehealth pricing changes frequently and varies by promotion, region, and plan tier. Henry Meds and Hims both run promotional campaigns that may temporarily lower costs for new patients, and some Henry Meds plans have historically included a separate consultation fee while others bundle it. Always verify current rates directly on each provider's website before committing.
Pricing Comparison: Where Your Money Actually Goes
Pricing is the primary reason patients compare Hims and Henry Meds, and the differences matter more than they might first appear. GLP-1 therapy isn't a one-month commitment — most patients need 6 to 12 months of continuous treatment to reach their weight loss goals, and many continue maintenance dosing well beyond that. Monthly cost differences that seem modest in isolation compound into hundreds or thousands of dollars over a full treatment course.
Hims prices compounded semaglutide at approximately $199/month and compounded tirzepatide between $199 and $249/month depending on plan. Consultations are generally included in the plan cost rather than billed separately, which simplifies the cost calculation — but the underlying monthly rate is still meaningfully higher than specialist alternatives.
Henry Meds prices compounded semaglutide at approximately $145/month and tirzepatide at approximately $199/month, generally bundled with no separate consultation fee — a genuine point in Henry Meds's favor relative to providers that layer fees on top of the advertised price. Even so, at $199/month for tirzepatide, Henry Meds still costs $34/month more than Luma Health's flat $165/month.
At Luma Health, compounded semaglutide costs $90/month and compounded tirzepatide costs $165/month, with no consultation fee, no enrollment fee, and no contract. A patient taking semaglutide for 12 months at Luma Health pays $1,080 total. The same patient at Hims pays approximately $2,388. The annual difference between Luma Health and Hims on semaglutide alone exceeds $1,300 — a gap that's difficult to ignore over a multi-year treatment course.
💡 Watch for hidden costs: When comparing GLP-1 providers, factor in consultation fees, dose-escalation pricing, shipping charges, and cancellation terms. A provider advertising a low headline rate but charging extra for the initial consultation, or increasing the rate at higher doses during titration, may cost more annually than a provider with one flat, all-inclusive rate at every dose tier.
Medications and Access: What Each Platform Offers
Both Hims and Henry Meds prescribe compounded versions of the two most clinically proven GLP-1 weight loss medications: semaglutide and tirzepatide. These compounded preparations use the same active ingredients found in the brand-name products Wegovy, Ozempic, Zepbound, and Mounjaro. Compounded medications are prepared per individual prescription by state-licensed pharmacies and are not themselves FDA-approved as drugs — the FDA's compounding guidance explains this regulatory framework in detail. The pharmacological effect of the active ingredient is the same regardless of which telehealth platform facilitates the prescription.
Hims offers both compounded semaglutide and compounded tirzepatide, though tirzepatide availability has varied over time depending on regulatory conditions and pharmacy capacity. Their platform distributes medications through an established network of compounding pharmacy partners built over years of operating across multiple health categories.
Henry Meds similarly offers both compounded semaglutide and compounded tirzepatide. As a more focused platform, Henry Meds has built pharmacy relationships specifically around weight loss medications, and their web-based system handles prescriptions and refills with medications shipped directly to patients.
Luma Health offers both compounded semaglutide and compounded tirzepatide as core offerings, dispensed by VialsRX, a licensed 503A sterile compounding pharmacy in Houston, TX, under prescription from Wasef Health, PC. Because Luma Health focuses specifically on metabolic health and GLP-1 therapy, medication supply continuity is a central operational priority rather than one product line among dozens. Patients who start with semaglutide and later want to transition to tirzepatide, or vice versa based on response and tolerability, can do so within the same platform and clinical relationship.
Provider Experience: Comparing Telehealth Models
The provider experience is where Hims and Henry Meds differ most meaningfully, and it's an aspect many patients underweight when choosing a GLP-1 platform. GLP-1 therapy involves dose titration decisions, side effect management, treatment duration planning, and ongoing clinical monitoring — all of which benefit from genuine provider expertise and engagement, not just speed of approval.
Hims operates primarily through an app-based, asynchronous model. Patients complete an online health questionnaire, a provider reviews the submission, and if appropriate, a prescription is issued without a live consultation. This approach is fast and convenient — many patients receive prescriptions within 24 to 48 hours. The trade-off is limited clinical dialogue. When you have questions about side effects or want to discuss dose adjustments, the asynchronous model can feel impersonal, and Hims providers cover dozens of unrelated health categories rather than specializing in metabolic health.
Henry Meds uses a web-based consultation system that may include more direct interaction during the initial evaluation phase, depending on plan. Ongoing provider interactions vary by plan and may diminish after the initial prescription is issued.
Luma Health's provider model centers on clinicians who focus specifically on weight management and metabolic health through Wasef Health, PC. This specialization matters for GLP-1 therapy because effective dose titration, side effect mitigation, and long-term treatment planning benefit from providers who manage these cases routinely rather than occasionally alongside dermatology and other unrelated specialties.
Clinical Background on GLP-1 Medications
GLP-1 receptor agonists are a class of medications originally developed for type 2 diabetes that have since demonstrated significant weight loss efficacy. Semaglutide (the active ingredient in Wegovy and Ozempic) and tirzepatide (the active ingredient in Zepbound and Mounjaro, a dual GIP/GLP-1 agonist) work by mimicking natural incretin hormones that regulate appetite, slow gastric emptying, and improve insulin sensitivity. In clinical trials, semaglutide produced average weight loss of approximately 15% of body weight at 68 weeks; tirzepatide produced up to approximately 22.5% at 72 weeks at the highest studied dose. Compounded versions of these medications contain the same active ingredients prepared by accredited pharmacies at a fraction of brand-name cost.
Eligibility Criteria
Licensed clinicians evaluate eligibility using FDA-aligned criteria: BMI ≥30, or BMI ≥27 with at least one weight-related comorbidity such as type 2 diabetes, hypertension, dyslipidemia, obstructive sleep apnea, or cardiovascular disease.
Contraindications
Personal or family history of medullary thyroid carcinoma, MEN 2 syndrome, pancreatitis, severe gastrointestinal disease, severe renal impairment, pregnancy, and breastfeeding are standard contraindications screened at intake by any reputable provider, including Hims, Henry Meds, and Luma Health.
Who Should Choose Which
Choose Hims if you value brand recognition and want weight loss bundled with other health categories you might also use, and consultation fees being included matters more to you than the lowest possible headline rate.
Choose Henry Meds if transparent, bundled pricing without a separate consultation fee is your top priority, and you're comfortable with a moderately higher monthly rate than the lowest-cost specialists.
Choose Luma Health if you want the lowest all-in monthly cost for compounded GLP-1 ($90–$165/month flat), a clinical team focused specifically on metabolic health rather than dozens of unrelated categories, and month-to-month flexibility with no contract.
Sources & References
- Wilding JPH, et al. "Once-Weekly Semaglutide in Adults with Overweight or Obesity" (STEP 1). NEJM. 2021;384:989–1002.
- Jastreboff AM, et al. "Tirzepatide Once Weekly for the Treatment of Obesity" (SURMOUNT-1). NEJM. 2022;387:205–216.
- FDA guidance on compounding regulations.
Frequently Asked Questions
Henry Meds is generally cheaper for semaglutide (approximately $145/month vs. Hims's $199/month), while tirzepatide pricing is closer between the two (roughly $199/month at both). Both remain more expensive than specialist flat-fee providers like Luma Health, which charges $90/month for semaglutide and $165/month for tirzepatide.
Yes. Both prescribe compounded semaglutide and compounded tirzepatide, the same active ingredients found in Wegovy, Ozempic, Zepbound, and Mounjaro. The medications themselves are pharmacologically equivalent regardless of which platform writes the prescription; the differences are in price, provider model, and clinical specialization.
Henry Meds's web-based model has historically allowed for somewhat more direct provider interaction during initial evaluation, while Hims operates primarily through an asynchronous app-based questionnaire model. Neither platform specializes exclusively in metabolic health, since both operate across multiple health categories — a structural difference from specialist providers like Luma Health.
Yes. Start Luma Health's intake first (5–10 minutes online) and confirm your prescription is approved and shipping before canceling your current provider. Share your current dose and titration history so Luma Health's clinical team can continue your treatment without restarting from the lowest dose.
Yes. Both are legitimate telehealth platforms using licensed providers and accredited compounding pharmacies. The comparison in this article is about cost, provider specialization, and platform model — not legitimacy. All three platforms discussed here, including Luma Health, deliver real medications under appropriate clinical oversight.